Backed by Science

FiberZ is supported by decades of scientific research on the benefits of dietary fiber. Discover clinically proven effects.

50+

Clinical studies

Peer-reviewed research

1,000+

Participants

In clinical trials

30+

Years

Of scientific research

95%

Tolerance

Without side effects

Why Is FiberZ Science-Based?

Resistant dextrin, the active component of FiberZ, is one of the most thoroughly researched forms of dietary fiber. It is recognized and approved by leading health organizations worldwide.

Key Scientific Findings

Prebiotic Fermentation & SCFA Production

Resistant dextrins are fermented in the colon, producing short-chain fatty acids (SCFAs) — butyrate, propionate, and acetate — which regulate appetite, stimulate immune cells, and enhance fatty acid oxidation in muscle tissue.


Source: Włodarczyk & Śliżewska, Nutrients, 2021

Improved Insulin Sensitivity

In clinical trials involving women with type 2 diabetes, 10g of daily resistant dextrin supplementation significantly decreased fasting insulin levels and reduced markers of inflammation and oxidative stress.


Source: Hu F. et al., 2020

Gut Microbiota Modulation

Resistant dextrin specifically increases the abundance of metabolically beneficial bacteria such as Prevotella and Akkermansia — primary drivers behind systemic improvements in glucose and lipid metabolism.


Source: Hu F. et al., 2020; Włodarczyk & Śliżewska, 2021

Cardiovascular & Blood Pressure Benefits

A 12-week randomized, double-blind, placebo-controlled trial in elderly T2DM patients showed significant reductions in both systolic and diastolic blood pressure, as well as improved postprandial glucose levels.


Source: Cai X. et al., 2018

Featured Clinical Studies

Milk Powder Co-supplemented with Inulin and Resistant Dextrin Improves Glycemic Control and Insulin Resistance in Elderly Type 2 Diabetes Mellitus

📅 2018🔬 Elderly T2DM patients 12 weeks

A randomized, double-blind, placebo-controlled trial examining the effects of milk powder co-supplemented with inulin and resistant dextrin (MPCIR) on glycemic control in elderly patients with type 2 diabetes mellitus.

Key Results:

  • Significant reductions in both systolic and diastolic blood pressure
  • Improved postprandial glucose levels
  • Enhanced insulin sensitivity markers

Cai X., Yu H., Liu L., Lu T., Li J., Ji Y., Le Z., Bao L., Ma W., Xiao R., Yang Y. (2018)

Efficiency of Resistant Starch and Dextrins as Prebiotics: A Review of the Existing Evidence and Clinical Trials

📅 2021🔬 Comprehensive review Multi-study

A comprehensive review evaluating the prebiotic efficiency of resistant starch and dextrins, their mechanisms of action through SCFA production, and their role in metabolic regulation, immune support, and fat oxidation.

Key Results:

  • SCFAs from fermentation regulate appetite via PYY and GLP-1 hormones
  • Stimulation of immune cells including T-helper cells and macrophages
  • Butyrate enhances fatty acid oxidation, reducing insulin resistance
  • ~75% of resistant dextrin reaches the large intestine for fermentation
  • Better tolerated than other fibers with less gas and bloating

Włodarczyk M., Śliżewska K. Nutrients (2021)

Combination of Inulin and Resistant Dextrin Has Superior Prebiotic Effects and Reduces Gas Production During In Vitro Fermentation

📅 2024🔬 Fecal samples from older adults In vitro

An in vitro fermentation study using fecal samples from older people to evaluate the synergistic prebiotic effects of combining inulin with resistant dextrin, focusing on gas production and microbiota diversity.

Key Results:

  • Combined inulin + resistant dextrin significantly reduced gas production
  • Maintained or increased microbiota diversity
  • Stimulated Bifidobacterium growth while minimizing bloating
  • Superior prebiotic effect compared to either fiber alone

Yoshida K., Kokubo E., Morita S., Sonoki H., Miyaji K. (2024)

Resistant Dextrin Improves High-Fat-High-Fructose Diet Induced Insulin Resistance

📅 2020🔬 Animal model + T2DM patients Multi-phase

A study examining how resistant dextrin ameliorates insulin resistance induced by high-fat-high-fructose diets, with clinical validation in women with type 2 diabetes using 10g daily supplementation.

Key Results:

  • Decreased fasting insulin levels in women with T2DM
  • Reduced markers of inflammation and oxidative stress
  • Promoted fatty acid β-oxidation in the liver
  • Reduced triglyceride (TG) and total cholesterol (TC) levels
  • Increased abundance of beneficial bacteria (Prevotella, Akkermansia)

Hu F., Niu Y., Xu X., Hu Q., Su Q., Zhang H. (2020)


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